UC – Urothelial carcinoma

Introduction

Since the introduction of PD-L1 as a biomarker for therapy with checkpoint inhibitors in non-small-cell lung carcinomas (NSCLC), further studies have been held on the correlation between expression of PD-L1 and carcinomas of other primary localizations. With a view to the urothelial carcinomas, not only the expression on the tumor cells, but also on the immune cells has been examined. As a function of the outcomes of these studies, registrations have already been given for various medications with varying scores and cut-offs.